Test Catalog

Service Code Test Name
LS110

4C Antibody Screen

Category: Antibody Screen & Identification | Service: TS,IRL

Category: Antibody Screen & Identification
Service: TS,IRL

Description: Red cell antibody screen and autocontrol performed 4C

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tube
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS010

ABO Discrepancy

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: Initial investigation of ABO blood typing discrepancies. 

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and/or clot tubes
Storage & Shipping: Shipping in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS005

ABO Grouping

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: ABO Group (serological), Forward and/or Reverse

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1 EDTA and/or clot tube
Storage & Shipping: Shipping in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
CT130

ABO Incompatibility Processing - Plasma Depletion

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Removal of Plasma

CT135

ABO Incompatibility Processing - Red Cell Depletion

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Removal of red cells from product received

LS050

ABO/Rh

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: Includes ABO grouping (forward and reverse) and Rh(D) typing

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1 EDTA and/or clot tube
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS205

Absorption Procedure

Category: Specialized Immunohematology Testing | Service: TS,IRL

Category: Specialized Immunohematology Testing
Service: TS,IRL

Description: Absorption procedure autologous or allogeneic per each adsorption tube.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
5745

ADAMTS-13 Activity

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: This assay is based on quantifying the cleavage of a small fragment of von Willebrand Factor by the ADAMTS-13 protease. The cleavage of this synthetic substrate is detected by reading the fluorescence that results when the substrate is cleaved.
 

Turnaround: Samples are batch tested, usually twice weekly.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma.)
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20°C or colder; ship on dry ice.
5913

ADAMTS-13 Autoantibody

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Detects IgG antibody serologically. Less specific than the functional assay. Positive results have been observed in people without severe ADAMTS-13 deficiency.

Turnaround: Samples are batch tested, usually every two weeks.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma.)
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20°C or less; ship on dry ice.
5954

ADAMTS-13 Inhibitor

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Functional assay to determine autoantibodies against ADAMTS-13 which is considered to be highly specific for TTP.  Low plasma levels of ADAMTS-13 activity (± 10%) and the presence of high titer inhibitor may be associated with poor prognosis.

Turnaround: Samples are batch tested, usually twice weekly.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20°C or less; ship on dry ice.
LS865 (17M)

Additional Wash, each

Category: | Service: IRL,TS

Category:
Service: IRL,TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
5665

Adenine Nucleotides

Category: Platelet Evaluation | Service: Coagulation Lab

Category: Platelet Evaluation
Service: Coagulation Lab

Description: An increase in the ATP/ADP ratio is consistent with a delta storage pool disorder.

Turnaround: Samples are batched tested, usually once or twice monthly.
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tubes at room temperature.
Storage & Shipping: Maintain specimen as whole blood at room temperature and transport to the laboratory immediately. Must be received in laboratory within 3 hours of collection. Do not chill, platelets are activated at low temperatures. DO NOT COLLECT SAMPLE BEFORE 7:00 a.m.!! Sample must be received in laboratory by 4:00 p.m.
6401

Adiponectin (Total)

Category: Platelet Evaluation | Service:

Category: Platelet Evaluation
Service:

Description:

LS875

Aliquot Preparation and Syringe, each

Category: | Service: TS

Category:
Service: TS

Description: Blood component aliquot preparation and syringe, each.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS870

Aliquot preparation, each

Category: | Service: TS

Category:
Service: TS

Description: Blood component aliquot preparation, each.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
6391

Angiopoietin-1

Category: | Service:

Category:
Service:

Description:

LS115

Antibody Identification Panel

Category: Antibody Screen & Identification | Service: TS,IRL

Category: Antibody Screen & Identification
Service: TS,IRL

Description: Routine or selected reagents RBC panel.  Autocontrol is included.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS120

Antibody Identification Panel, Rare

Category: Antibody Screen & Identification | Service: TS,IRL

Category: Antibody Screen & Identification
Service: TS,IRL

Description: Rare, selected reagent RBC panel up to 6 cells, each panel set up.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and/or clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS105

Antibody Screen, each

Category: Antibody Screen & Identification | Service: TS,IRL

Category: Antibody Screen & Identification
Service: TS,IRL

Description: Red Cell antibody screen/detection, any methodology and or additive

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
537R

Anticardiolipin Antibodies (IgG, IgM)

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Evaluate patients with prolonged PTT and thrombotic tendency, including patients with systemic lupus erythematosus, recurrent spontaneous abortion of early pregnancy, and suspected antiphospholipid antibody syndrome.

Turnaround: 2 days (excludes weekends and holidays)
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
542l

Anticardiolipin IgA

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Evaluate patients with prolonged PTT and thrombotic tendency, including patients with systemic lupus erythematosus, recurrent spontaneous abortion of early pregnancy, and suspected antiphospholipid antibody syndrome.

Turnaround: Batch tested once weekly
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS810 (23M)

Antigen Typing, Donor - Confirmed or Historical, per Antigen.

Category: | Service: IRL,TS

Category:
Service: IRL,TS

Description: Donor common red cell antigen typing, per antigen.

Turnaround: Depends upon request; See TAT description
Sample Requirements: Unit segments or 1 EDTA tube
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS815 (24M)

Antigen Typing, Donor, Rare - Confirmed or Historical, per Antigen

Category: | Service: IRL,TS

Category:
Service: IRL,TS

Description: Donor rare red cell antigen typing, per antigen

Turnaround: Depends upon request; See TAT description
Sample Requirements: Unit segments or 1 EDTA tube
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS025

Antigen Typing, Patient, per Antigen

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: Antigen typing of patient RBC's (serologic), per antigen

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1 EDT and/or clot tube
Storage & Shipping: Shipping in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS030

Antigen Typing, Patient, Rare per Antigen

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: Rare antigen typing of patient RBC's (serologic).  Rare antigen examples (not all inclusive): k, Kpa, Cw, Yta, etc.,

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1 EDTA and/or clot tube
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
547X

AntiphosphatidyIserine Antibodies (IgG, IgM)

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Antiphospholipid antibodies are a group of very heterogenous autoantibodies with reactivity against various negatively charged phospholipids, including phosphatidylserine, cardiolipin and others.  The clinical importance of antiphospholipid is their strong association with recurrent venous and arterial thrombosis, thrombocytopenia, and fetal abortion.  Antiphosphatidylserine testing uses an indirect ELISA format to detect antibodies in human serum or plasma.  Since autoimmune antiphospholipid antibodies require a cofactor (B2-glycoprotein l) for optimal binding, a source of cofactor is included for increased detection of clinically relevant antibodies.  The concentration of both lgG and lgM type phosphatidylserine antibodies are determined and reported out separately.  The clinical specificity of the aPS assay is comparable to the specificity of the anticardiolipin (aCL) assay.

Turnaround: Batch tested once weekly
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5651

Antiphospholipid Antibodies (lgG, lgM)

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Anti-phospholipid testing uses an indirect ELISA format to detect antibodies.

Turnaround: Batch tested once weekly
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536A

Antiplasmin Activity

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Measure the amount of the major inhibitor of plasmin(ogen) in the fibrinolytic system.

Turnaround: Batch tested once weekly
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5365

Antithrombin lll Activity

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Evaluate response to heparin, hypercoagulable, and fibrinolytic states; test for hereditary deficiency of antithrombin lll.  Antithrombin levels are of use in cases of suspected heparin failure, DIC or personal or familial history of thromboembolic disease.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
547C

APC Resistance

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Screening assay to determine the presence of the Factor V Leiden mutation

Turnaround: 7 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6327

Apixaban Level

Category: Functional | Service:

Category: Functional
Service:

Description:

5363

APTT (Activated Partial Thromboplastin Time)

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Useful screening test to detect factor deficiencies or inhibitors of the intrinsic pathway of coagulation.  Also used to monitor heparin therapy.  The APTT will prolong when: 1) there are deficiencies of factors II, V, VIII, IX, X, XI and XII ; 2) an inhibitor to a specific clotting factor is present; or 3) a non specific inhibitor of the intrinsic pathway (heparin or lupus anticoagulant) is present

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
535S

APTT (Activated Partial Thromboplastin Time) Mix

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Plasma is incubated 1:1 with Normal Pool for 60 minutes at 37℃, to detect the presence/absence of an inhibitor.  Incubated mixes are performed to increase inhibitor detection.  Recommend ordering APTT with APTT Mix.  NOTE: For meaningful interpretation, this test should not be ordered without also ordering the APTT.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS955 (54M)

ASAP Delivery Fee

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description: Fee for ASAP delivery of blood products.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS915

ASAP Request

Category: Other Services | Service: IRL,TS

Category: Other Services
Service: IRL,TS

Description: ASAP patient workup.  Special urgency for patient testing workup or Antigen negative requested by client.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
CT300

Base Lab Processing of Peripheral Blood Progenitor Cells and Bone Marrow After Hours

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Base lab processing from 2300 to 0600, weekends and holidays.

CT100

Base Lab Processing of Peripheral Blood Progenitor Cells and Bone Marrow (Autologous & Allogeneic)

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Processing, splitting and labeling additional bags from original collection.  Includes testing for CD34, CD3, Total Nucleated Count, Manual Differential, Sterility, Viability, Infectious Disease Markers and cryopreservation of up to 6 bags for storage up to 36 months.

5652

Beta 2 Glycoprotein Antibodies (IgG, IgM, IgA)

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Antiphospholipid antibodies are a heterogenous group of autoantibodies associated with the clinical manifestations of APS.  These antibodies frequently require the presence of a serum protein as cofactor for optimal in vitro binding activity forming phospholipid-protein complexes.  Binding of B2GPI directly to a microtiter plate has been found to produce antigenic sites like those produced when bound to phospholipid.  This assay minimizes the variability observed between classic antiphospholipid ELISAs (cardiolipin and phosphatidylserine bound to plastic, with exogenous source of cofactor).  In addition, studies indicate anti-B2GPI antibodies are more specific for thrombosis than antibodies detected by anticardiolipin ELISAs.  Specifically, it has been suggested by various research groups that anti-B2GPI may help to distinguish "infectious" from "autoimmune" antiphospholipid antibodies.  Only autoimmune antiphospholipid antibodies are associated with thrombosis.  Anti-B2GPI testing uses an ELISA format to detect antibodies in human plasma.  The IgG type anti-B2GPI antibodies are generally regarded as the most clinically significant isotype

Turnaround: Batch tested twice weekly
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS965

Blood Bank Arm Bands, per box

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS945

Blood Product Administration set, each

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description: Blood product administration set, each

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS445

Blood Type Recheck

Category: Compatibility Testing | Service: TS

Category: Compatibility Testing
Service: TS

Description: Patient ABO/Rh(D) confirmation from a 2nd specimen for transfusion of blood products.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 7 mL EDTA tube, no red top Serum Separator
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
HL700

Buccal Swab DNA Isolation

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: Isolation of highly purified DNA from a buccal swab sample for HLA testing.

CT170

CAR-T Processing & Cryopreservation

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Base processing of product for CAR-T manufacture, including priority processing status.  Includes CD3 enumeration, TNC, viability, manual differential, sterility testing, cryopreservation and short-term storage of cryopreserved product.  Storage to include pre-manufacture and post-manufacture prior to distribution for infusion.  

CT200

CD34 Enumeration and Viability

Category: Transplant | Service: CTL

Category: Transplant
Service: CTL

Description: Determination of absolute count, percentage, and viability of CD34 progenitor cells in peripheral blood, pheresis product or bone marrow by flow cytometry.

6364

Cell/Plasma Repository

Category: Transplant | Service:

Category: Transplant
Service:

Description: This is a storage opportunity for client samples. Inquire within.

HL600

Chimerism Studies

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: Testing of post transplant blood samples for percentage mixture of donor and patient DNA.Pre

551I

Closure Time (Platelet Function Screen)

Category: Platelet Evaluation | Service: Coagulation Lab

Category: Platelet Evaluation
Service: Coagulation Lab

Description: Platelet dysfunction may be acquired, inherited, or induced by platelet inhibiting agents.  The most common causes of platelet dysfunction are related to uremia, von Willebrand's disease (vWD), and exposure to agents such as acetyl salicylic acid (ASA, aspirin).  Current methods to assess platelet function include Closure Time (CT) and aggregation studies.  The PFA-100 is an instrument and test cartridge system in which the process of platelet adhesion and aggregation following a vascular injury is simulated in vitro.  This system allows for rapid evaluation of platelet function on samples of anticoagulated whole blood.  Using biologically coated membranes Collagen/Epinephrine (CEPI) and Collagen/Adenosine-5'- diphosphate (CADP) and high shear rates generated under standardized flow conditions, platelet plug formation at the aperture can be evaluated.  The time required to obtain full occlusion of the aperture is reported as the Closure Time (CT) in seconds.

Turnaround: 1 day
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tubes at room temperature.
Storage & Shipping: Maintain specimen as whole blood at room temperature and transport to the laboratory immediately. Must be received in laboratory within 3 hours of collection. Do not chill, platelets are activated at low temperatures. DO NOT COLLECT SAMPLE BEFORE 7:00 a.m.!! Sample must be received in laboratory by 4:00 p.m.
LS845 (40M)

CMV Negative, per Component

Category: | Service: IRL,TS

Category:
Service: IRL,TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
537J

Coagulation Factor Profile

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Includes Factors II, V, VII, X, VIII, IX, XI, XII, PT, PT Mix, APTT, APTT Mix

Turnaround: 1 day
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (min. 2 mL platelet poor plasma)
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS280

Cold Agglutinin Titer

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Titer of cold reactive autoantibodies (per titer).

Turnaround: Depends upon request; See TAT description
Sample Requirements: Call for special collection instructions
Storage & Shipping: Call for special collection instructions
5922

Collegen Binding Assay

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Quantitates the collagen binding capacity of vWF to collagen-coated microtiter wlls.  The CBA may correlate more closely with vWF function than vW antigen and/or vW Multimer testing.

Turnaround: Batch tested; contact lab for availability
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
CT210

Colony Forming Units (CFU)

Category: Processing Tests | Service: CTL

Category: Processing Tests
Service: CTL

Description: Culture of hematopoietic progenitor cells (HPCs) includeing erythroid, myeloid and megakaryocytic.

LS410

Compatibility Screen

Category: Compatibility Testing | Service: IRL,TS

Category: Compatibility Testing
Service: IRL,TS

Description: Compatibility screen is not the crossmatch test of record and unit is not tagged.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
CT215

Complete Blood Count

Category: Processing Tests | Service: CTL

Category: Processing Tests
Service: CTL

Description: Total nucleated cell count, hemotocrit and a breakout of mononuclear cell and granulocyte percentages.

CT105

Cord Blood Dilution - No Wash (with pre & post CD34)

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Dilution of DMSO from cord product with CD 34 testing.

CT105

Cord Blood Dilution - No Wash (without CD34)

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Dilution of DMSO from cord product.

LS420

Crossmatch : Antiglobulin (AHG)

Category: Compatibility Testing | Service: TS

Category: Compatibility Testing
Service: TS

Description: Antiglobulin Crossmatch by any Methodology

Turnaround: Depends upon request; See TAT description
Sample Requirements: 7 mL EDTA tube, no red top Serum Separator
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS425

Crossmatch: Electronic (EXM)

Category: Compatibility Testing | Service: TS

Category: Compatibility Testing
Service: TS

Description:

Turnaround: Depends upon request; See TAT description
Sample Requirements: 7 mL EDTA tube, no red top Serum Separator
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS415

Crossmatch: Immediate Spin (IS)

Category: Compatibility Testing | Service: TS

Category: Compatibility Testing
Service: TS

Description: IS Crossmatch by any methodology

Turnaround: Depends upon request; See TAT description
Sample Requirements: 7 mL EDTA tube, no red top Serum Separator
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS440

Crossmatch: Remote Electronic

Category: Compatibility Testing | Service: TS

Category: Compatibility Testing
Service: TS

Description:

Turnaround: Depends upon request; See TAT description
Sample Requirements: 7 mL EDTA tube, no red top Serum Separator
Storage & Shipping: None
LS825 (43M)

Crossmatched Platelet tagging, per component.

Category: | Service: IRL,TS

Category:
Service: IRL,TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
536B

Cryofibrinogen

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect and quantitate cold precipitable fibrinogen.

Turnaround: Batch tested
Sample Requirements: One 10 mL green top (heparin) tube or two 4.0 mL (Min. 2 mL plasma).
Storage & Shipping: Maintain at room temperature (20℃ or 25℃) and process within 2 hours. Incubate at 37℃ for 10 minutes; mix well by gentle inversion, then spin at room temperature; freeze plasma.
547B - Single Cryo 6352-pooled Cryo

Cryoprecipitate Product QC

Category: Quality Control | Service: Coagulation Lab

Category: Quality Control
Service: Coagulation Lab

Description: Test includes: Factor VIII:C, Fibrinogen. 
 Evaluate whether blood products meet the standards of the blood banking industry.

Turnaround: 3 days
Sample Requirements: One bag or aliquot tube of cryoprecipitate, in compliance with your standard operating procedure. Criteria for Rejection: Broken bag/tube.
Storage & Shipping: Freeze at -70℃ or less: ship on dry ice.
5997

Dabigatran (Pradaxa) Level

Category: Drug Monitoring | Service: Coagulation Lab

Category: Drug Monitoring
Service: Coagulation Lab

Description: Use quantitative measurement of Pradaxa (Dabigatran), a Direct Thrombin Inhibitor (DTI), in citrated plasma as an aid in the management of patients receiving Dabigatran.  Used to manage bleeding in cases of possible excess anticoagulant activity, patients with renal insufficiency, recurrent TIA/CVA symptoms despite therapeutic dose, and to ensure patient compliance.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS295

DAT NEG AIHA Evaluation

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: DAT negative Hemolytic anemia investigation (other names) Immune Hemolytic Anemia Evaluation: Micro Coombs; Super Coombs.  (Send out).

6376

DIC (Disseminated Intravascular Coagulation) Screen

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Tests include: PT, PT Mix; APTT; APTT Mix; Fibrinogen; Thrombin Time; Reptilase Time (if needed, will invoke additional charge); FDP (plasma); Quant d-Dimer; Antithrombin III Activity; Physician interpretation with clinical recommendations if warranted.

Turnaround: 1 day
Sample Requirements: Four 3.5 mL blue top (3.2% sodium citrate) tubes. (Min. 4 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS040

Direct Antiglobulin Test

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: DAT test. 

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1 EDTA tube
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS265

Donath-Landsteiner Test

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Diagnostic test of Paroxysmal Cold Hemoglobinuria (PCH).

Turnaround: Depends upon request; See TAT description
Sample Requirements: Call for special collection instructions.
Storage & Shipping: Call for special collection instructions.
LS830

Donor Antigen screening, 1-10 units screened

Category: | Service: IRL,TS

Category:
Service: IRL,TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS270

Drug Dependent Antibody Studies

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Test for identification of drug dependant antibodies.

Turnaround: Depends upon request; See TAT description
Sample Requirements: Call for special collection instructions
Storage & Shipping: Call for special collection instructions
535B

dRVVT (Dilute Russell Viper Venom Time)

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Antiphospholipid antibodies directed against anionic phospholipids or phospholipid-protein complexes that interfere with phospholipid dependent in vitro coagulation assays are known as lupus anticoagulants (LACs). LACs are a significant risk factor in patients with otherwise unexplained thrombosis and are often present in women who have recurrent miscarriages. Patients are referred for LAC work-up due to an abnormal screening test of hemostasis, usually a prolonged APTT or based on clinical symptoms. Russell’s Viper Venom (dRVV) selectively activates factor X to Xa, with factor V and phospholipid, activates factor II to thrombin. By diluting the phospholipid and RVV, this assay becomes very sensitive to lupus anticoagulant. On addition of phospholipid, a relative correction or neutralization of LAC results in a shorter clotting time. The new assay is a twostep procedure that includes a dRVV screen and a confirmatory step. The result is reported as a ratio of Screen clotting time (seconds)/ Confirm clotting time (seconds) and results greater than 1.1 are positive for a lupus anticoagulant. The improved reagents contain polybrene to neutralize the effect of heparin. As a result, the dRVV ratio is a more specific test for the evaluation of LAC than APTT.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6135

D-Dimer Quantitative

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Used to evaluate chronic or acute disseminated intravascular coagulation (DIC), acute myocardial infarction, and unstable angina.  SUITABLE AS EXCLUSION TEST TO RULE OUT DVT OR PE.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS225

Elution Procedure

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Procedure performed to remove antibodies from the surface of red blood cells.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS125

Enzyme Panel - Manufactured

Category: Antibody Screen & Identification | Service: TS,IRL

Category: Antibody Screen & Identification
Service: TS,IRL

Description: Testing of manufactured enzyme-treated RBC panel.  Autocontrol is included.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and/or clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS220

Enzyme Treatment

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Pre-modification/treatment of RBC's using proteolytic enzymes (i.e., Ficin, Papain, etc.,)

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
536C

Euglobulin Lysis

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect and evaluate pathological fibrinolytic activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
547Y

Factor Assays

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Includes Factors II, V, VII, X, IX, XI, XII

Turnaround: 1 day
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (min. 2 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536E

Factor II

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Quantity specific coagulation factor activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
535I

Factor Inhibitor

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Specimen must be received before day of testing.
Please note Factor on requisition.
Recommend prior Factor activity testing.

Used to evaluate patients with an inhibitor to a Factor other than Factor VIII: C or Factor IX.  Client must specify which Factor is to be studied.  This Factor Activity must be <25% normal (.025 U/mL) to distinguish inhibitor activity.

Turnaround: 7 days (batch tested twice weekly)
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (min. 2 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536J

Factor IX

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect specific coagulation factor IX activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
537U

Factor IX Inhibitor

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Specimen must be received before day of testing.
Used to evaluate patients with inhibitors to Factor IX.  Recommend prior Factor IX Activity testing.  The Factor IX activity must be <25% (0.25 U/mL) to distinguish inhibitor activity.

Turnaround: 7 days
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (min. 2 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6269

Factor IX Inhibitor (H-I Nigmegen Method)

Category: Functional | Service:

Category: Functional
Service:

Description:

536F

Factor V

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect specific coagulation factor activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6250

Factor V Antigen (Total)

Category: Functional | Service:

Category: Functional
Service:

Description:

5591

Factor V HR-2 Haplotype

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: Researchers have actively studied the factor V gene to determine the cause of APCr in the 5-10% of patients that do not carry the Leiden mutation.  Recently, eidence has emerged that shows that Factor V genetic components other than the Leiden mutation contribute to the APCr phenotype and are associated with increased thrombotic risk.  A polymerase chain reaction (PCR) based assay amplifies an 828 bp fragment of the factor V genomic DNA containing the R2 allele.  The amplified fragment is then restriction endonuclease digested using Rsa I.  Digest fragments are separated by agarose gel electrophoresis to allow detection and discrimination of homozygosity of heterozygosity for the polymorphism in the factor V gene.

Turnaround: Batch tested every two weeks Average: 14-18 days. Max: 28 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
557F

557F Factor V Leiden Mutation (F5: c.1601G>A (p.Arg534GIn or R534Q; legacy nomenclature: c.1691G>A)

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: Of the inherited causes of VTE, the Factor V Leiden variant is the most prevalent. Heterozygosity for this variant occurs in ~1/20 Caucasians (5%) and homozygosity in ~1/1200 Caucasians. However, this variant is highly enriched in patients with unprovoked VTE, being identified in 20-50% of individuals with VTE and no identifiable acquired risk factor. Circumstantial risk factors including pregnancy, the use of oral contraceptives, trauma and surgery may also increase the thrombotic risk in both heterozygous and homozygous cases.  The genetic variant in FVL is a single nucleotide change that eliminates one of two cleavage sites for Activated Protein C (APC), resulting in slower inactivation of the active FV molecule.  The F5 gene variant responsible for FVL is c.1601G>A (p.Arg534GIn or R534Q); legacy nomenclature: c.1691G>A (p.ARG506GIn or R506Q).

Turnaround: Batch tested once weekly; Average: 7 days; Max: 21 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
536G

Factor VII

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect specific coagulation factor activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5963

Factor VIIa

Category: Functional | Service:

Category: Functional
Service:

Description:

6249

Factor VIII Antigen

Category: Functional | Service:

Category: Functional
Service:

Description:

537T

Factor VIII Inhibitor

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Specimen must be received before day of testing. Used to evaluate patients with inhibitors to Factor VIII. Recommend prior Factor VIII Activity testing. The Factor VIII activity must be <25% (0.25 U/mL) to distinguish inhibitor activity.

Turnaround: 7 days (batch tested twice weekly)
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (min. 2 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5364

Factor VIII: C

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect coagulant Factor VIII deficiency.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536H

Factor X

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect specific coagulation Factor X activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
537l

Factor X Chromogenic

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: The chromogenic factor X assay is the method of choice for oral anticoagulant monitoring in patients with lupus anticoagulants affecting the prothrombin time.  A therapeutic range of factor X is established by correlation to the appropriate target INR range (2.0 - 3.5).  This assay is insensitive to the effects of lupus anticoagulants and can provide monitoring for effective anticoagulant therapy and improved patient management.  The chromogenic factor X assay indirectly measures the level of the vitamin K dependent factor X in human plasma.  This is done in two stages.  In the first stage factor X is activated in the presence of calcium to Factor Xa by the activator Russell's Viper Venom (RVV).  In the second stage the generated factor Xa hydrolyzes a chromogenic substrate resulting in a color change.  The intensity of the color change is proportional to the factor X activity in the sample.  This assay does not require a phospholipid membrane surface and is insensitive to the effects of a phospholipid antibody.

Turnaround: 7 days (batch tested twice weekly)
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5386

Factor XI Inhibitor

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Specimen must be received before day ot testing.

Used to evaluate patients with an inhibitor to factor XI.  If a prolonged APTT fails to correct after an incubated mix with normal plasma and factor analysis reveals a marked decrease in factor XI only, a specific factor XI inhibitor is suspected.  A titer to quantitate the amount (strength) of the inhibitor, such as the Bethesda assay, is useful in patient management and to monitor the success in eradicating the inhibitor.

Turnaround: Batch tested twice weekly
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (min. 2 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6056

Factor XIa

Category: Functional | Service:

Category: Functional
Service:

Description:

536L

Factor XII

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect specific coagulation factor XII activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5387

Factor XII Inhibitor

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Specimen must be received before day of testing. Used to evaluate patients with inhibitors to Factor XII. Recommend prior Factor XII Activity testing. The Factor XII activity must be <25% (0.25 U/mL) to distinguish inhibitor activity.

Turnaround: 7 days (batch tested twice weekly)
Sample Requirements: Two 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 2 mL frozen platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6289

Factor XIII Activity - Quantitative

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: The FXIII Activity test is an assay that quantitatively determines the patient's FXIII functional ability.  The previous FXIII Antigen method only measured the amount of FXIII protein present in the sample rather than the patient's FXIII functional capabilities.  Therefore, the newer FXIII Acitivity-Quantitative assay may be more useful than the discontinued antigen method.  In addition, the new FXIII Activity- Quantitative test is more specific than qualitative assays for FXIII, such as clot lysis methods (FXIII screen), since these clot lysis tests can only detect FXIII abnormalities below 1-2%.

Turnaround: Batch tested once weekly
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536K

Factor XI

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect specific coagulation factor XI activity.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536M

Factor XIII Screen - Qualitative

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: A Factor XIII deficiency of less than 1-2% can be detected by this in vitro method. 

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
537P

Fibrin Degradation Products

Category: Functional | Service:

Category: Functional
Service:

Description:

5373

Fibrinogen

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Identify congenital afibrinogenemia or hyprofibrinogenemia.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536U

Fibrinogen Antigen

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Specimen must be received before day of testing.

Turnaround: 11 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5962

Fibrinopeptide A

Category: Serological | Service:

Category: Serological
Service:

Description: Special sample requirements. Inquire within.

HL200

Flow Crossmatch

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: HLA T & B Cell crossmatch by flow cytometry for transplant donor selection.

5762

Fondaparinux (Arixtra) Level

Category: Drug Monitoring | Service: Coagulation Lab

Category: Drug Monitoring
Service: Coagulation Lab

Description: Used to monitor Fondaparinux (Arixtra) levels in patients.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
CT105

Fresh Allogeneic Processing without cryopreservation, Bone Marrow or Peripheral Blood Progenitor Cells

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Base lab processing services and testing for fresh products listed.

6362

FVIII (Chromogenic method)

Category: Autologous & Allogeneic Stem Cells | Service:

Category: Autologous & Allogeneic Stem Cells
Service:

Description:

6363

FVIII Inhibitor (Chromogenic method)

Category: Autologous & Allogeneic Stem Cells | Service:

Category: Autologous & Allogeneic Stem Cells
Service:

Description:

5607

Glycoprotein la C807T

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: The GPIa/IIa complex mediates platelet adhesion to collagen.  Although the GPIa C807T polymorphism does not change the amino acid sequence, it has been associated with the difference in the GPIa/IIa receptor levels on the platelet surface.  Carriers of the 807T allele express higher levels of GPI/IIa, while carriers of the 807C allele exhibit lower expression of the integrin.  This polymorphism has been implicated to be associated with an increased risk of arterial thrombosis.  Additional studies suggested this is a mild risk factor and is particularly important in synergism with known risk factors such as smoking, hypertension, diabetes, or proteinuria, which may enhance its contribution to the overall cardiovascular risk.  Detection is through PCR amplification and RFLP agarose gel electrophoresis.

Turnaround: Contact lab for testing schedule Average: 14-18 days Max: 35 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
LS285 (41M)

Hemoglobin S

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Sickle cell screen test.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 2 EDTA tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
547L

Heparin Level/Anti-Xa

Category: Drug Monitoring | Service: Coagulation Lab

Category: Drug Monitoring
Service: Coagulation Lab

Description: An approach to assay for heparin is by exploiting its catalysis by antithrombin III inhibition of coagulation enzymes, particularly factor Xa.  In this method, factor Xa is present in excess and the residual factor Xa activity is inversely proportional to the heparin concentration.  Unlike assays based on thrombin, this assay is based on factor Xa and is sensitive to both standard and low molecular weight (LMW) heparins

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma). Type of heparin for evaluation MUST be provided to the laboratory (e.g., Unfractionated, Lovenox, Fragmin or Innohep).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
550B

Heparin PF4 (Platelet Factor 4) Antibody

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: HIT occurs when Heparin triggers the formation of antibodies directed at a Heparin-platelet factor 4 complex. This complex binds to platelet Fc receptors resulting in platelet activation, platelet aggregation, platelet granule release and the formation of procoagulant microparticles that accelerate thrombin generation.  The identification of platelet factor4 (PF4) as the target component, allowed the design of the ELISA assay for the diagnosis of heparin induced thrombocytopenia.  This assay incorporates the use of coated wells with PF4 complexed with heparin.  Prediluted plasma containing heparin-PF4 antibodies will bind to the wells if present.  A second conjugated affinity-purified Anti-human IgG, M and A will bind to the complex and the intensity  of observed coloration is directly proportional to the antibodies present in the test sample.  Most of the diagnostic methods for type II HIT are based on the use of platelet aggregometry tests or serotonin release assay (SRA).  The platelet aggregation method requires careful selection of control platelets and lacks sensitivity and specificity.  The SRA, considered by many to be the gold standard, also requires carefully selected control platelets, radioisotopes and is difficult to perform.  The heparin-PF4 ELISE assay has similar sensitivity to SRA and is reproducible and relatively easy to perform.  Studies have shown that heparin-PF4 ELISA yields false negative results in approximately 10% of patients tested with clinically evident HIT.

Turnaround: 3 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL frozen platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
535H

Heparin Platelet Antibody (Aggregation Method)

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Heparin-Induced Platelet Antibody

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL frozen platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
550C

Heparin Platelet Antibody Panel

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: refer to 535H and 550B

557T

Hereditary Hemochromatosis HFE C282Y

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: Hereditary hemochromatosis is a genetically determined disorder characterized by iron overload.  The carrier frequency for this mutation may be as high as 1 in 15 among people of European descent.  A point mutation in the HFE gene results in Cys282Tyr substitution.  This substitution has been identified as the major genetic defect for this autosomal recessive inherited disorder.  Most affected individuals are homozygous for the mutant allele, although a few may be heterozygous with variable phenotypic expression.  Molecular detection of the mutation can lead to early diagnosis and treatment to prevent the long-term sequalae of iron overload.  DNA analysis for a specific nucleotide change is performed by a PCR reaction coupled with the binding of a probe to homologous sequence, otherwise knows as TaqMan SNP Genotyping technology.  Two probes are present in the reaction, each conjugated to a different fluorophore:  one binds the reference allele and surrounding sequence with high affinity, and one binds the variant allele and surrounding sequence with high affinity.  Each probe is also conjugated to a quencher, which prevents emission of the fluorescent signal when it is near fluorophore.  Probe bound to the template sequence is cleaved during amplification.  This releases the quencher from the probe, which can then emit fluorescent signal. Fluorescent signals are quantified in a PCR well with instrumentation capable of detecting emissions that occur due to probe binding to the reference or variant sequence.  This is what allows the instrument to determine the genotype of an individual at a specific nucleotide.

Turnaround: Batch tested every two weeks Average: 10-14 days Max: 28 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
558D

Hereditary Hemochromatosis HFE H63D

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description:  SAME as  557T

Turnaround: Batch tested every two weeks Average: 10-14 days Max: 28 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
547A

Hexagonal Phospholipid Neutralization

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Antiphospholipid antibodies (including the so-called lupus anticoagulant) have been associated with an increased risk of recurrent thromboses, fetal loss and thrombocytopenia. LAC's are usually detected because they inhibit phospholipid dependent coagulation tests, such as the APTT, PT and dilute RVV.  They presumably do this by binding to phospholipids, not to individual coagulation factors.  Due to the heterogeneity of composition and potency of LAC's, there is no single test that is able to detect all positive individuals.  Hexagonal Phase Neutralization Assay utilizes Antiphospholipid antibodies from human hybridomas which were produced from patients with lupus.  These monoclonal antibodies are able to bind to hexagonal (II) phase phosphatidylethanolamine (HPE), but not lamellar (bilayer) phosphatidylethanolamine (PE).  The hexagonal phase neutralization assay is based on the findings that HPE will bind to lupus anticoagulants, thus inhibiting their actions.  The test features a dilute APTT reagent with decreased lipids that is highly sensitive to LAC's.  The patient plasma is mixed with an equal volume of normal plasma.  If the clotting time with the addition of HPE is 8 or more seconds less than the mix without HPE, then the test is considered positive for LAC.  This test is an important addition to our LAC profile, because it may be used for patients on oral anticoagulants or heparin. 

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL frozen platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
HL305

HLA (A, B) IR for Apheresis Platelet Donors

Category: Platelet Transfusion Support,Blood Donor Typing | Service: HLA

Category: Platelet Transfusion Support,Blood Donor Typing
Service: HLA

Description: DNA based assay provides intermediate resolution (2 digits) of HLA-A, B alleles.  Typing  apheresis donor is required prior to donating for HLA matched platelets.

HL700

HLA (A, B) IR for Patient Platelet Transfusions

Category: Platelet Transfusion Support | Service: HLA

Category: Platelet Transfusion Support
Service: HLA

Description: DNA based assay provides intermediate resolution (2 digits) typing of HLA-A-B alleles,  Typing required for patient before search for HLA matched platelets.

HL500

HLA (A, B, C, DR, DRB3/4/5, DQA, DQB, DPA & DPB) ) HR for Patient or Donor Typing

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: Next Generation Sequencing (NGS) and/or DNA based assay for HLA Class I & II alleles provides a high=resolution HLA genotype for new transplant patients and their potential donors.

HL300

HLA (A, B, DR) IR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay provides initial intermediate resolution (2 digit) typing of HLA A, B, DR for preliminary assessment of histocompatibility in siblings of transplant recipient.

HL120

HLA Antibody ID Class II

Category: HLA Antibody ID | Service: HLA

Category: HLA Antibody ID
Service: HLA

Description: Idenification of antibody specificities to HLA Class II (DR, DQ, DP) antigens by Luminex microbead array methodology.

Turnaround: 3 business days
Sample Requirements: 10 mL clotted whole blood in red to tube.
Storage & Shipping: Blood specimens may be kept at room temperature and shipped at room temp or 24℃ up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4℃ and shipped up to 7 days from date of draw.
HL545

HLA Class I (A, B, C) HR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay used to achieve definition at high resolution (4 digits) of Class I HLA-A, B, C alleles.

HL545

HLA Class I (A, B, C) IR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay provides intermediate resolution (2 digits) assignment of Class I HLA-A, B, C alleles.

HL455

HLA Class I Single Locus IR (e.g., B*27)

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: Adults (normal WBC): 10-20 mL EDTA: Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Cord blood sample: 0.5 mL; Buccal swabs are acceptable.

HL415

HLA Class II (DR, DQ, with or without DPB) IR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay provides low to intermediate resolution (2 digits) assignment of Class II HLA DR, DQ alleles.

HL460

HLA Class II single Locus IR (e.g., DQ2, DQ8)

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based typing of any single locus provides intermediate resolution (2 digits) typing to determine presence or absence of 1 or 2 antigens/alleles named by client for disease association or research purposes.

HL550

HLA class II Typing (DR, DRB3/4/5, DPA, DPB, DQA & DQB) HR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay provides high resolution (4 digits) typing of  HLA, DRB1, DRB3/4/5, DPA, DPB, DQA and DQB1 alleles.

JL555

HLA DPA 1 HR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay to provide high resolution (4 digits) typing of HLA DPA1 alleles.

HK540

HLA DPB1 HR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay provides high resolution (4 digits) typing of  HLA, DPB1 alleles.

HL560

HLA DQA1 HR

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: DNA based assay to provide high resolution (4 digits) typing of HLA DQA1 alleles.

LS805 (42M)

HLA Matched Platelet Fee, per component

Category: Donor or Unit Fees | Service: IRL,TS

Category: Donor or Unit Fees
Service: IRL,TS

Description:

Turnaround: Depends upon request; See TAT description
Sample Requirements: N/A
Storage & Shipping: N/A
HL900

HLA Priority Services

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: Reduced reporting time arranged by lab supervisor.

HL905

HLA STAT After Hours

Category: Transplant | Service: HLA

Category: Transplant
Service: HLA

Description: Reduced reporting time arranged by lab supervisor.

536N

HMW Kininogen (Fitzgerald Factor)

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Investigate the causes of prolonged APTT; identify HMW Kininogen deficiency (Fitzgerald Factor deficit).

Turnaround: 10 days; Availability is variable (dependent on deficient plasma availability).  
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS850 (73M)

Irradiation Fee

Category: Donor or Unit Fees | Service: IRL,TS

Category: Donor or Unit Fees
Service: IRL,TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS287

Kleihauer-Betke, Quantitative

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Kleihauer-Betke (KB) - is used to determine the volume of fetomaternal hemorrhage to estimate the amount of rhig needed to prevent alloimmunization.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
CT105

Labeling Extra bags after the 6th

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Utilizing extra bags during processing for product storage, including labeling.

547T

Lupus Anticoagulant (LAC) Panel

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Test includes: PT; APTT; APTT Mix; dRVV; Thrombin Time; Reptilase Time (if needed; will invoke additional charge); Tissue Thromboplastin Inhibition (TTI); Factor VIII:C; Hexagonal Lipid Neutralization; Anticardiolipin Antibodies (IgG, IgM); Anti-VIII (if needed; will invoke additional charge), and Physician interpretation with clinical recommendation if warranted.   LAC Panel includes screening and confirmatory tests to detect the presence of phospholipid antibodies that may be associated with thrombosis.  Normal test results do not necessarily rule out a lupus anticoagulant.

Turnaround: 2 days
Sample Requirements: Three 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 3 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5774

Lupus Anticoagulant (LAC) Panel II

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: LAC Panel II includes screening and confirmatory tests (see 547T above; also includes Beta 2 Glycoprotein I) to detect the presence of phospholipid antibodies that may be associated with thrrombosis.  Normal test results do not necessarily rule out a lupus anticoagulant.

Turnaround: 2 days
Sample Requirements: Three 3.5mL blue top (3.2% sodium citrate) tubes. (Min. 3 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
547S

Lupus Anticoagulant (LAC) Screen

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Test includes:  PT; APTT; APTT Mix; dRVV; Thrombin Time; Reptilase time (if needed; will invoke additional charge); Tissue thromboplastin Inhibition (TTI); and Interpretation.  Basic screen to detect the presence of phospholipid antibodies that may be associated with thrombosis.  Normal test results do not necessarily rule out a lupus anticoagulant.

Turnaround: 2 days
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (Min. 2 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
CT105

Manual Differential - on product received at BSL

Category: Processing Tests | Service: CTL

Category: Processing Tests
Service: CTL

Description: Manual white blood cell count differential.

LS505

Molecular Extended Red Cell Genotype/Phenotype

Category: Red Cell and Platelet Molecular Testing | Service: IRL,TS

Category: Red Cell and Platelet Molecular Testing
Service: IRL,TS

Description: Molecular determination of allelic variants that determine common rare red cell antigens using multiplex PCR and microarray analysis. (Send out). 

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1-2 EDTA tubes (unspun and unopened)
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS510

Molecular Genotype pe-Platelet (HPA)

Category: Red Cell and Platelet Molecular Testing | Service: IRL,TS

Category: Red Cell and Platelet Molecular Testing
Service: IRL,TS

Description: Molecular determination of allelic variants that determine common Human Platelet Antigens, using multiplex PCR and microarray analysis.  (Send out).

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1-2 EDTA tubes (unspun and unopened)
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS525

Molecular Sequencing Test

Category: Red Cell and Platelet Molecular Testing | Service: IRL,TS

Category: Red Cell and Platelet Molecular Testing
Service: IRL,TS

Description: Gene sequencing.  Send out to a specialized genomics laboratory. LS525 covers non-RH sequencing, i.e., sequencing for ABO, LU, JK and other genes.  (Send out).

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1-2 EDTA tubes (unspun and unopened)
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS292

Monocyte Monolayer Assay (MMA)

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Monocyte Monolaer Assay used to better predict the transfusion risk of a clinically significant antibody. (Send out).

557Y

MTHFR Gene Variant A1298C

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: A deficiency in the methylenetetrahydrofolate reductase (MTHFR) enzyme, as well as deficiencies in folate, vitamin B12 and B6 can result in elevated homocysteine levels in the blood.  Moderate homocysteinemia has been associated with thrombosis (venous and arterial), coronary disease and cerebrovascular disease.  Homocysteine is believed to induce endothelial cell damage and promote platelet adhesion. Hetero - or homozygosity for MTHFR (A1298C) alone does not increase thrombotic risk but does increase risk when combined with hetero or homozygosity with the C677T variant.

Turnaround: Batch tested once weekly Average: 5-7 days Max: 14 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
557X

MTHFR Gene Variant C677T

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: A deficiency in the methylenetetrahydrofolate reductase (MTHFR) enzyme, as well as deficiencies in folate, vitamin B12 and B6 can result in elevated homocysteine levels in the blood.  Moderate homocysteinemia has been associated with thrombosis (venous and arterial), coronary disease and cerebrovascular disease.  Homocysteine is believed to induce endothelial cell damage and promote platelet adhesion.  In vitro, it has been shown to activate clotting factors on the surace of endothelial cells and inhibit the activation of protein C. Additionally, it has been reported that patients who have both the Factor V Leiden mutation as well as homocysteinemia, have an increased risk of thrombosis, greater than having either defect alone.

Turnaround: Batch tested once weekly Average: 5-7 days Max: 14 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
LS905

On-Call fee

Category: Other Services | Service: IRL,TS

Category: Other Services
Service: IRL,TS

Description: On-call fee.  Apply to patient testing workup or Antigen negative request outside of regularly staffed business hours.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
5620

PAI-1 (Plasminogen Activator Inhibitor) 4G/5G Polymorphism

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: PCR-based assay that amplifies a fragment of the genomic DNA.  Amplified fragment are detected directly by agarose gel electrophoreseis.

Turnaround: Contact lab for testing schedule Average: 14-18 days Max: 35 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
547P

PAI-1 (Plasminogen Activator Inhibitor-1) Activity

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Quantitates the activity of PAI-1 in the plasma.  An increased plasma level of PAI is an important reason for impaired fibrinolytic function and may be associated with thrombotic disease.  Increased levels have been found in pregnancy and sepsis.

Turnaround: 28 days; Availability is variable.
Sample Requirements: One 3.5mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5391

PAI-1 (Plasminogen Activator Inhibitor-1) Antigen

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Quantitates the amount of human plasminogen activator inhibitor-1 antigen in the plasma.  The clinical utility of the assay is to detect disorders  of the fibrinolytic system.

Turnaround: 28 days; Availability is variable.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS275

Pathological Cold Agglutinin Screen

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Test to evalute the clinical significance of cold reactive autoantibodies.

5621

PL A1/A2 Polymorphism

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: Platelet membrane Glycoprotein IIb/IIIa, a receptor for fibrinogen and von Willebrand's factor, plays a major role in platelet function.  An association of the PLA2 allele with increased platelet aggregability in vitro has been described and several studies have linked this marker to cardiovascular disease.

Turnaround: Contact lab for testing schedule Average: 14-18 days Max: 35 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
LS435 (57M)

Plasma Thawing

Category: Compatibility Testing | Service: TS

Category: Compatibility Testing
Service: TS

Description: Thawing of Plasma for transfusion purposes.

6344

Plasma-Alpha-2-Antiplasmin (PAP) Complex

Category: Compatibility Testing | Service:

Category: Compatibility Testing
Service:

Description:

537A

Plasminogen Activity

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Determine plasminogen and plasmin activity in plasma; study of dysplasminogen; monitor thrombolytic therapy; evaluate DIC.

Turnaround: 7 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5358

Platelet Aggregation Panel

Category: Platelet Evaluation | Service: Coagulation Lab

Category: Platelet Evaluation
Service: Coagulation Lab

Description: Test includes:  Platelet Aggregations with 7 agonists (3 concentrations of ADP - 20uM, 10uM, 5uM; Collagen; 2 concentrations of Ristocetin - 1.2 mg, 0.3 mg; and Arachidonic Acid) and interpretation.  Evaluate platelet function; aid in diagnosis of von Willebrand disease, Glanzmann's disease, platelet storage pool disease, Bernard-Soulier syndrome, "gray platelet syndrome" and Raynaud's phenomenon.

Turnaround: 1 day
Sample Requirements: Five 3.5 mL blue top (3.2% sodium citrate) tubes at room temperature.
Storage & Shipping: Maintain specimen as whole blood at room temperature and transport to the laboratory immediately. Must be received in the Vitalant Coagulation Laboratory within 3 hours of collection. Do not chill, platelets are activated at low temperatures. DO NOT COLLECT SAMPLE BEFORE 7:00 a.m!!! Sample must be received in laboratory by 4:00 p.m.
LS310

Platelet Antibody Screen Test

Category: Platelet Antibody Testing | Service: IRL,TS

Category: Platelet Antibody Testing
Service: IRL,TS

Description: Platelet Antibody detection by solid phase methods.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 10 mL EDTA tube(s)
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS305

Platelet Crossmatch Test

Category: Platelet Antibody Testing | Service: IRL,TS

Category: Platelet Antibody Testing
Service: IRL,TS

Description: Platelet crossmatch by solid phase methods, per strip tested.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 10 mL EDTA tube(s)
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
547Z

Platelet Function Panel

Category: Platelet Evaluation | Service: Coagulation Lab

Category: Platelet Evaluation
Service: Coagulation Lab

Description: Sample must be received in laboratory by 4:00 p.m. 
Test includes:  Platelet Aggregations with 5 agonists (3 concentrations of ADP - 20uM, 10uM, 5uM; Collagen; and Arachidonic Acid) and an interpretation, may be added to a von Willebrand Profile without duplication of tests. 
Evaluate platelet function; aid in diagnosis of Glanzmann's disease, platelet storage pool disease, Bernard-Soulier syndrome, "gray platelet syndrome" and Raynaud's phenomenon.

Turnaround: 2 days
Sample Requirements: Four 3.5mL blue top (3.2% sodium citrate) tubes at room temperature.
Storage & Shipping: Maintain specimen as whole blood at room temperature and transport to the laboratory immediately. Must be received in the Vitalant Coagulation Laboratory within 3 hours of collection. Do not chill, platelets are activated at low temperatures. DO NOT COLLECT SAMPLE BEFORE 7:00 a.m!!! Samples must be received in laboratory by 4:00 p.m.
LS260

Polyagglutination Screen

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Screen test for polyagglutination.  Includes testing with human sera and lectins, if available.

536P

Prekallikrein (Fletcher Factor)

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Availability is variable

Turnaround: 7 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS130

Prewarm Setup

Category: Antibody Screen & Identification | Service: TS,IRL

Category: Antibody Screen & Identification
Service: TS,IRL

Description: Prewarm setup requires the aliquoting and warming of patient plasma, RBC's, saline and other reagents prior to testing.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and/or clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
535Q

Protein C Activity

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Protein C is a vitamin k-dependent protein, primarily synthesized in the liver.  Circulating Protein C is converted to an active protease, activated Protein C (APC), by the action of thrombin in the presence of the endothelial cell cofactor thrombomodulin.  Upon activation, anticoagulant activity of PC is expressed only after the formation of a functional complex that consists of a phospholipid surface, factor V and free Protein S.  In the procoagulant pathway, the Protein C/Protein S activated complex inhibits coagulation by inactivating factors Va and VIIIa rendering them nonfunctional.  The functional assay for Protein C is based on the ability of Protein C in a patient's plasma to prolong the clotting time of an APTT reaction reconstituted with Protein C deficient plasma.  Thus, this assay tests for the activity of Protein C on its natural substrates (Factors Va and VIIIa).  Patient samples that are shown to have a deficiency in biologic function that cannot be attributed to liver disease or anticoagulant therapy can be further characterized with an antigenic assay for confirmation of the defect.  This functional assay replaces a chromogenic assay previously used to screen for Protein C deficiencies.  The clotting endpoint functional assay more accurately reflects Protein C function in vivo.

Turnaround: 4 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
537Q

Protein S Activity

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: One major and important regulatory system with both anticoagulant and fibrinolytic properties is the Protein C system.  This system consists of a complex collection of plasma proteins that interact with vessels and platelets to inhibit coagulation.  Protein C (PC) and Protein S (PS) are the central components of this system, which when either is significantly decreased, will predispose an individual to an increased risk for thromboembolic disease.  The functional assay for Protein S is based on the ability of protein S to serve as a cofactor for activated protein C in a Factor V dependent clotting assay (reconstituted with Protein S deficient plasma).  Cleavage of activated Factor V by activated Protein C with Protein S as a cofactor will prolong the clotting time.  This assay detects only free Protein S which is the active form of this molecule.  Protein S functional assays can detect low protein levels and dysfunctional or inactivated molecules.  The appropriate antigenic assay is recommended to confirm and further characterize a detected abnormality.

Turnaround: 4 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
537M

Protein C Antigen

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Investigate patients with thromboses, especially venous thromboses in young adults; study patients with hypercoagulable  state.  Protein C antigen measures total protein C functional and immunoreactive.  Order in conjunction with Protein C activity to determine and type deficiency.

Turnaround: 11 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536I

Protein S Total Antigen

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Availability is variable.

Turnaround: 28 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5705

Protein S. Free Antigen

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Patients on oral anticoagulants may have decreased functional protein C/S values.  For accurate testing results, the patient should be off anticoagulant therapy (coumadin) for two weeks.

Turnaround: 14 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5677

Prothrombin Fragment 1+2

Category: Research Use Only | Service: Coagulation Lab

Category: Research Use Only
Service: Coagulation Lab

Description: Used as an aid for diagnosis, monitoring and evaluating acquired or hereditary blood coagulation disorders, especially in the assessment of risk of thrombosis.  It may also be used in monitoring anticoagulant therapy.  Elevated levels of PT F 1+2 may be found in patients with thrombosis, pulmonary embolism, DIC, trauma, and sepsis.  Levels of PT F 1+2 may also be elevated in patients with hereditary thrombophilia with Factor V Leiden or Protein C or Protein S deficiencies.  Patients undergoing oral anticoagulant therapy or heparin therapy may show significant decreases in PT F 1+2 levels.

Turnaround: Availability is variable. Maximum turn around time is 21-28 days.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
557V

Prothrombin Gene Variant

Category: Genetic | Service: Coagulation Lab

Category: Genetic
Service: Coagulation Lab

Description: Venous Thromboembolism is a significant medical problem for approximately 1 in 1000 people in the general population.  A genetic point mutation in the prothrombin gene (G20210A) has been identified as an additional risk factor for venous thrombosis.  The mutation in the prothrombin gene is located in the 3' untranslated (noncoding) region of  the gene and results in a G to A transition at position 20210.  Prothrombin is also known as Factor II.  It is the precursor of thrombin, which late in the clotting cascade leads to the formation of fibrin.  The prothrombin gene mutation (G2021A) leads to elevated levels of prothrombin in plasma and is associated with an increased risk of venous thrombosis.  The frequency of this allele has been reported to be 1-2% in the general population.  Among patients with venous thrombotic episodes or a family history of venous thrombotic episodes, the prevalence has been reported to be 6-20%.  The role of the prothrombin gene variant in arterial disease is not yet known and is currently under investigation.  Patient lymphocytes are processed to extract DNA.  Using 250 ng of human DNA, a polymerase chain reaction (PCR) is performed to amplify a 118 bp fragment of the gene encoding the prothrombin protein.  The 118 bp fragment includes the G20210A transition site which has been associated with increased prothrombin levels and venous thrombosis.  The amplimer is restriction enzyme digested with the enzyme Taq 1 to identify and enable genotypic analysis of the G2010A polymorphism.  Enzyme digest fragments are resolved on a 3.0% agarose gel and visualized by ethidium bromide staining.  The 118 bp product of the wild type allele yields fragments of 98 bp and 20 bp.  The mutant allele is not susceptible to digestion by Taq 1 and yields a 118 bp fragment.

Turnaround: Batch tested once weekly Average: 5-7 days Max: 14 days
Sample Requirements: One 7 mL yellow top (ACD) tube preferred. EDTA (purple-top) or sodium citrate (blue-top) also acceptable. Minimum 2.0 mL Whole blood. Should be received within 3 days of collection.
Storage & Shipping: Room temperature as whole blood, must be received in lab within 3 days of collection.
5359

PT (Prothrombin time)

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Evaluate extrinsic coagulation system; screen for congenital deficiencies of factors II, V, VII, X; deficiency of prothrombin; dysfibrinogenemia (complete); coumadin or warfarin effect; liver failure; disseminated intravascular coagulation (DIC); screen vitamin K deficiency.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
535P

PT (Prothrombin time) Mix

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect the presence of an inhibitor.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS835 (18M)

Rare Unit Fee

Category: Donor or Unit Fees | Service: IRL,TS

Category: Donor or Unit Fees
Service: IRL,TS

Description: Fee for each product issued or shipped that meets the "rare" criteria.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS235

Red Cell Separation Method

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description:

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS215

Red Cell Stroma-Alloadsorption

Category: Specialized Immunohematology Testing | Service: TS,IRL

Category: Specialized Immunohematology Testing
Service: TS,IRL

Description: Alloadsorption using Papain-treated human red cell stroma or RESt stroma, for each adsorption tube.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS240

Red Cell Separation - Percoll

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description:

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS210

Red Cell Treatment

Category: Specialized Immunohematology Testing | Service: TS,IRL

Category: Specialized Immunohematology Testing
Service: TS,IRL

Description: Chemical pre-modification of red cells for testing.  (i.e., EGA/CHL/DTT/WARM)

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
537D

Reptilase® Time

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Distinguish hypofibrinogenemia from heparin contamination and fibrin split products (FSP's).

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS020

Rh Phenotype

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: Rh typing (serological) for all 4 common Rh antigens C, c, E and e

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1 EDTA and/or clot tube
Storage & Shipping: Shipping in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS015

Rh(D) Typing

Category: Red Cell Testing | Service: TS,IRL

Category: Red Cell Testing
Service: TS,IRL

Description: Rh(D) Typing (Serologic)

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1 EDTA and/or clot tube
Storage & Shipping: Shipping in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS515

Rh(D) Genotype Test

Category: Red Cell and Platelet Molecular Testing | Service: IRL,TS

Category: Red Cell and Platelet Molecular Testing
Service: IRL,TS

Description: Gene sequencing. Send out to a specialized genomics laboratory.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1-2 EDTA tubes (unspun and unopened)
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS520

RHCE Genotype Test

Category: Red Cell and Platelet Molecular Testing | Service: IRL,TS

Category: Red Cell and Platelet Molecular Testing
Service: IRL,TS

Description: Gene sequencing.  Send out to a specialized genomics laboratory.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 1-2 EDTA tubes (unspun and unopened)
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS975

Rho (D) Immune Globulin, each

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
537N

Ristocetin CoFactor Activity

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Evaluate von Willebrand factor activity.  Differential diagnosis between hemophilia and von Willebrand's disease.

Turnaround: 6 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6095

Rivaroxaban Level

Category: Functional | Service:

Category: Functional
Service:

Description:

LS290

Rosette Test, Qualitative

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Screening test for fetomaternal hemorrhage.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS135

Saline Replacement Setup

Category: Antibody Screen & Identification | Service: TS,IRL

Category: Antibody Screen & Identification
Service: TS,IRL

Description: Saline replacement (SR) setup. SR is a technique used to disperse suspected rouleaux in the patient plasma/serum sample.

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS930 (50M)

Sample/Material Handling Fee

Category: Other Services | Service: IRL,TS

Category: Other Services
Service: IRL,TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS920

Send out Testing

Category: Other Services | Service: IRL

Category: Other Services
Service: IRL

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
CT105

Sepax Cord Blood Product wash (per bag)

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Automated cord blood washing, in a functionally closed sytstem.

LS245

Serum Neutralization/Inhibition Procedure

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description:

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS250

Serum Treatment with Chemical Agents

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description:

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
LS970

Specimen hold, each

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description:

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
5648

Spontaneous Platelet Aggregation

Category: Other Services | Service:

Category: Other Services
Service:

Description:

5648

Spontaneous Platelet Aggregations

Category: Platelet Evaluation | Service: Coagulation Lab

Category: Platelet Evaluation
Service: Coagulation Lab

Description: Detect hyperaggregability of platelets.

Turnaround: 2 days
Sample Requirements: Four 4.5 mL blue top (3.2% sodium citrate) tubes at room temperature.
Storage & Shipping: Maintain specimen as whole blood at room temperature and transport to the laboratory immediately. Must be received in laboratory within 4 hours of collection. Do not chill, platelets are activated at low temperatures. DO NOT COLLECT SAMPLE BEFORE 7:00 a.m!! Sample must be received in laboratory by 4:00 p.m.
LS940 (65M)

STAT Delivery fee

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description: Fee for STAT delivery of blood products.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS910

STAT request

Category: Other Services | Service: IRL,TS

Category: Other Services
Service: IRL,TS

Description: STAT patient workup. Urgency for patient testing workup or Antigen negative request (move to front of the line) requested by client.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
CT220

Sterility

Category: Processing Tests | Service: CTL

Category: Processing Tests
Service: CTL

Description: Bacterial and fungal cultures on product.

LS960

Stocking Fee for Emergency Services Providers

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description: Fee applied to emergency services provider and TF with on-hold RBC inventory.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
CT220

Storage of Peripheral Blood Progenitor Cells and Bone Marrow

Category: Storage with or without Cryopreservation | Service: CTL

Category: Storage with or without Cryopreservation
Service: CTL

Description: Stem Cell Storage, per bag, with no processing or cryopreservation up to 36 months.

CT220

Storage of Peripheral Blood Progenitor Cells and Bone Marrow with cryopreservation

Category: Storage with or without Cryopreservation | Service: CTL

Category: Storage with or without Cryopreservation
Service: CTL

Description: Cryopreservation for each bag over 6 with storage up to 36 months.

6328

Syndecan-1

Category: Storage with or without Cryopreservation | Service:

Category: Storage with or without Cryopreservation
Service:

Description:

5676

TAT (Thrombin-Antithrombin) Complex

Category: Research Use Only | Service: Coagulation Lab

Category: Research Use Only
Service: Coagulation Lab

Description: Used in the evaluation of patients for thrombosis and DIC; some patients may have elevated levels of TAT.  Also, TAT is important in patients with multiple trauma, liver dysfunction, septicemia and preeclampsia.  TAT may rise in patients with advanced state malignancies.  TAT may increase during the course of heparin and fibrinolysis therapy.

Turnaround: 1 day
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
CT120

T-Cell Therapeutic Processing

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Base lab processing services and testing and up to 36 months of cryopreservation for up to 6 bags.

LS255

Thermal Amplitude Test

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description: Testing to determine cold antibodies optimal temperature of reactivity.

Turnaround: 24 hours
Sample Requirements: Call for special collection instructions
Storage & Shipping: Call for special collection instructions
6090

Thrombin Generation Assay

Category: Specialized Immunohematology Testing | Service:

Category: Specialized Immunohematology Testing
Service:

Description:

537E

Thrombin Time

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Determine severe hypofibrinogenemia and presence of heparin-like anticoagulants; diagnose and monitor DIC and fibrinolysis; monitor thrombolytic therapy.  A reptilase time will be performed to evaluate fibrinogen when thrombin time is prolonged.  The need to do the Reptilase time will invoke an additional charge.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5975

Thrombomodulin

Category: Research Use Only | Service: Coagulation Lab

Category: Research Use Only
Service: Coagulation Lab

Description: Thrombomodulin is found on the endothelial surface and is known to bind thrombin and the thrombin-thrombomodulin complex is a strong activator of Protein C to Activated Protein C (APC).  APC is a well-known protein involved in limiting the coagulation response and thus, decreased thrombomodulin may lead to less APC and increased risk of thrombosis.

 

Turnaround: Availability is variable.  Maximum turn around time is 21-28 days.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5974

Thrombospondin (TSP-1)

Category: Research Use Only | Service: Coagulation Lab

Category: Research Use Only
Service: Coagulation Lab

Description: TSP-1 is released from platelet granules during platelet activation.  In association with von Willebrand Factor (vWF) and fibrinogen, TSP-1 contributes to clot formation.  TSP-1 has been shown to inhibit angiogenesis and minimize new vessel growth.
 

Turnaround: Availability is variable.  Maximum turn around time is 21-28 days.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
547V

Thrombotic Risk Screen

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Test includes:  APC Resistance:  Antithrombin III Activity; Protein C Activity; Protein S Free Antigen; Factor X and a  Interpretation.

Turnaround: 7 days
Sample Requirements: Three 3.5mL blue top (3.2% sodium citrate) tubes. (Min. 3mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5982

Tissue Factor Activity

Category: Research Use Only | Service: Coagulation Lab

Category: Research Use Only
Service: Coagulation Lab

Description: Tissue Factor (TF) is also known as Coagulation Factor III or   Thromboplastin and its is found on sub-endothelial cells.  It plays a critical role in triggering blood coagulation by binding to Factor VIIa to form a Factor VIIa-TF complex.  This complex then cleaves Factor X to FXa and Factor IS to FIXa to help initiate the coagulation cascade.  The level of TF may be increased in malignancies, inflammation, atherosclerosis, sepsis, diabetes, sickle cell disease and acute coronary syndrome.  During sepsis, increased activation of the coagulation mechanism may result from enhanced cytokine-medicated expression of TF on endothelial cells and monocytes.  In atherosclerotic plaques, TF ruptures various pro-coagulant material including microparticles containing TF.  TF may also play a significant role in angiogenesis and metastasis.

Turnaround: Availability is variable. Maximum turn around time is 21-28 days.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
5981

Tissue Factor Pathway Inhibitor (Free)

Category: Research Use Only | Service: Coagulation Lab

Category: Research Use Only
Service: Coagulation Lab

Description: TFPI inhibits the extrinsic coagulation pathway by forming a complex of TFPI-FXa-Tissue Factor (TF)-FVIIa.  Most of the TFPI is bound to the endothelial cell surface and two forms of TFPI are found in plasma (lipoprotein-associated TFPI and free TFPI).  Only the free form is associated with any anticoagulant activity.  TFPI can also be found in platelets and is released with any anticoagulant activity.  TFPI can also be found in platelets and is released during platelet activation.  TFPI is closely related to total and HDL-cholesterol levels.  TFPI levels are higher in men than women, especially for the free form.  TFPI is also released into circulation following heparin injections.

Turnaround: Availability is variable.  Maximum turn around time is 21-28 days.   
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6167

Tissue Factor Pathway Inhibitor (Total)

Category: Research Use Only | Service: Coagulation Lab

Category: Research Use Only
Service: Coagulation Lab

Description: TFPI inhibits the extrinsic coagulation pathway by forming a complex of TFPI-Fxa-Tissue Factor (TF)-FVIIa.  Most of the TFPI is bound to the endothelial cell surface and two forms of TFPI are found in plasma (lipoprotein-associated TFPI and free TFPI).  Only the free form is associated with any anticoagulant activity.  TFPI can also be found in platelets and is released with any anticoagulant activity.  TFPI can also be found in platelets and is released during platelet activation.  TFPI is closely related to total and HDL-cholesterol levels.  TFPI levels are higher in men than women, especially for the free form.  TFPI is also released into circulation following heparin injections.

Turnaround: Availability is variable.  Maximum turn around time is 21-28 days.   
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS230

Titration Studies, per Titration

Category: Specialized Immunohematology Testing | Service: IRL,TS

Category: Specialized Immunohematology Testing
Service: IRL,TS

Description:

Turnaround: N/A
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
5388

tPA Antigen

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Quantitates the amount of human tissue type plasminogen (tPA) antigen in the plasma.  The clinical utility of the assay is to detect disorders of the fibrinolytic system.

Turnaround: Availability is variable.
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
LS925

Transfusion facility or emergency service provider initial setup fee.

Category: Other Services | Service: TS

Category: Other Services
Service: TS

Description: Initial assessment fee charged to transfusion facility or emergency service provider [ESP/ED] that requests Vitalant services.

Turnaround: N/A
Sample Requirements: N/A
Storage & Shipping: N/A
LS710

Transfusion reaction evaluation - Physician

Category: Physician Services | Service: TS

Category: Physician Services
Service: TS

Description: Transfusion reaction investigation, interpretation and written report, Physician services.

LS705

Transfusion reaction investigation - Clerical

Category: Physician Services | Service: TS

Category: Physician Services
Service: TS

Description: Transfusion reaction investigation - Clerical.  

Turnaround: Depends upon request; See TAT description
Sample Requirements: 4 EDTA and 1 clot tubes
Storage & Shipping: Shipped in a container maintaining temperature between 1 -10℃ (preferred). Room temperature acceptable.
CT225

Trypan Blue Viability

Category: Processing Tests | Service: CTL

Category: Processing Tests
Service: CTL

Description: Simple dye exclusion test to measure the percentage of viable white cells.

Turnaround: 2 hours; M-F 8am - 8pm
Sample Requirements: 0.5 mL of anticoagulant HPC product
Storage & Shipping: Shipped at 1 -10℃
535G

TTI (Tissue Thromboplastin Inhibition)

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Detect lupus-like anticoagulants.  Prolonged prothrombin times invalidate the tissue thromboplastin inhibitor test.

Turnaround: 2 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
6402

VEGFR1

Category: Functional | Service:

Category: Functional
Service:

Description:

CT125

Volume Reduction

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Reduce plasma as required for cryoprservation purposes.

5356

von Willebrand Profile

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Test includes:  Factor VIII:C; Ristocetin CoFactor (RCoF activity); vW Antigen; APTT; APTT Mix; Ristocetin Induced Platelet Aggregations; Closure Time: vW Antigen Multimer Analysis (if needed), will invoke additional charge and an interpretaton with clinical recommendations if warranted.  

Diagnosis and typing of von Willebrand's disease.

Turnaround: 10 days
Sample Requirements: Three 3.5 mL blue top (3.2% sodium citrate) tubes. (Min. 3 mL platelet poor plasma). Two 3.5 mL blue top (3.2% sodium citrate) tubes at room temperature.
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice. Room temperature tubes must be received in the laboratory within 4 hours of collection AND by 4:00 p.m.
536V

von Willebrand Screen

Category: Functional | Service: Coagulation Lab

Category: Functional
Service: Coagulation Lab

Description: Test includes:  APTT; APTT Mix; Factor FVIII:C; Ristocetin CoFactor Activity; von Willebrand Antigen; vW Antigen Multimers (if needed, will invoke additional charge); and a comment.

Screen provides diagnostic information and typing for von Willebrand's disease.

Turnaround: 10 days
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
536R

vW Ag Multimer Analysis

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Classify von Willebrand disease

Turnaround: 10 days
Sample Requirements: Two 3.5mL blue top (3.2% sodium citrate) tube. (Min. 2 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
537F

vW Antigen

Category: Serological | Service: Coagulation Lab

Category: Serological
Service: Coagulation Lab

Description: Von Willebrand antigen measures total plasma vWF, functional and immunoreactive.  Usually ordered as part of von Willebrand Profile.  This test alone does not rule out von Willebrand disease.  Useful in the differential diagnosis of hemophilia A and von Willebrand disease.

Turnaround: 6 days
Sample Requirements: One 3.5 mL blue top (3.2% sodium citrate) tube. (Min. 1 mL platelet poor plasma).
Storage & Shipping: Separate plasma within one hour of collection and freeze at -20℃ or less; ship on dry ice.
CT145

Wash - Manual (with pre & post CD34)

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Thawing of previously frozen harvest with washing and CD34 testing.

CT150

Wash - Manual (without CD34)

Category: Autologous & Allogeneic Stem Cells | Service: CTL

Category: Autologous & Allogeneic Stem Cells
Service: CTL

Description: Thawing of previously frozen harvest with washing.